Bacterial/Permeability-Increasing Protein, Human Neutrophil (BPI, CAP57)

PRODUCT NUMBER:

MW 55,000
Extinction Coefficient - 1.0

Frozen in 50 mM Tris buffer, pH 8.0, with 800 mM NaCl.

Storage: -70°C or lower

Buy Purified Native Bacterial/Permeability-Increasing Protein (BPI,CAP57), Human Neutrophil.
Price $150.00/1x100ug. Bulk Qty Available.

Bacterial/Permeability-Increasing Protein (BPI) is present in the azurophilic granules of polymorphonuclear leukocytes (PMN). BPI is toxic only toward Gram-negative bacteria. This specificity is attributable to the strong attraction of BPI for the lipopolysaccharides (LPS) in the bacterial envelope. BPI is also an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis.

Purity: >=95% by SDS-PAGE

Ref: Zhao M.H., Jones S.J., and Lockwood C.M.. Clin Exp Immunol 1995. 99, 49. Elsbach P., and Weiss J. Immunobiology 1993. 187, 417.

Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.