Cathepsin S, Human Spleen

PRODUCT NUMBER:

This product is NOT recombinant.

MW 24,000
Extinction Coefficient - 1.0

Lyophilized from 100 mM Na Acetate, pH 5.5, 1 mM EDTA.

Storage: -20°C

Buy Purified Native Human Cathepsin S (CatS), Human Spleen.
Price $100.00/1x25ug. Bulk Qty Available.

Like Cathepsins B, H, and L, Cathepsin S belongs to the group of lysosomal cysteine proteases. Cathepsin S is found primarily in the spleen and in lung macrophages. Its level is elevated in the brain tissue of those with Alzheimer's disease and Down syndrome. Cathepsin S may function in the processing of amyloid precursor protein to amyloid beta peptides.

Activity: Cathepsin S activity detected using Z-Val-Val-Arg-AMC (Bachem: I-1540)

Ref: Shi, G.P., et al. 1994. J. Biol. Chem. 15, 11530. Lemere, C.A., et al. 1995. Am J. Pathol. 146(4): 848. Munger, J. S., et al. 1995. Biochem. J. 311: 299.

Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.