(BPI; 57kD antimicrobial cationic protein, CAP57)
Product Number 16-14-021609

MSDS

Price

Packaged 100 ug per vial

MW 55,000

Frozen in 50 mM Tris buffer, pH 8.0, with 800 mM NaCl.

Storage: -70°C or lower

Bacterial/Permeability-Increasing Protein (BPI) is present in the azurophilic granules of polymorphonuclear leukocytes (PMN). BPI is toxic only toward Gram-negative bacteria. This specificity is attributable to the strong attraction of BPI for the lipopolysaccharides (LPS) in the bacterial envelope. BPI is also an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis.

Purity: >=95% by SDS-PAGE

Ref: Zhao M.H., Jones S.J., and Lockwood C.M.. Clin Exp Immunol 1995. 99, 49. Elsbach P., and Weiss J. Immunobiology 1993. 187, 417.

Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.





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