Ceruloplasmin, Human Plasma

1 mg
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MW: 132,000
Extinction Coefficient: 1.5

Lyophilized from 50 mM potassium phosphate, pH 6.8, 100 mM KCl and 20 mM E-amino-n-caproic acid + 5 mM EDTA.

Storage: <= -20°C

Buy Purified Native Human Ceruloplasmin, Human Plasma direct from the manufacturer.

An acute-phase reactant. Increased levels are associated with normal pregnancy, rheumatoid arthritis, and cirrhosis. Decreased levels are associated with hepatolenticular degeneration (Wilson's Disease). An elevated level of Cp is found in patients with progressive tumors. Additionally, as Cp is a prooxidant, an elevated level is a sign of cardiovascular disease.

Purity: >=95% by SDS-PAGE

Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.

Product Citations:
Zhi, Wenbo, Meiyao Wang, and Jin‐Xiong She. "Selected reaction monitoring (SRM) mass spectrometry without isotope labeling can be used for rapid protein quantification." Rapid Communications in Mass Spectrometry 25, no. 11 (2011): 1583-1588.
Zhao, Xue-Jun, Ling Wang, Sruti Shiva, Jesus Tejero, Jun Wang, Sam Frizzell, and Mark T. Gladwin. "Mechanisms for Cellular NO Oxidation and Nitrite Formation in Lung Epithelial Cells." Free Radical Biology and Medicine (2013)
Hermann G, Møller LH, Gammelgaard B, Hohlweg J, et al.
In vivo synthesized 34 S enriched amino acid standards for species specific isotope dilution of proteins.
J Anal At Spectrom. 2016; 31(9):1830-1835. DOI: 10.1039/C6JA00039H

Ref: Deutsch, HF, Kasper, CB and Walsh, DA 1962 Arch Biochem Biophys 99, 132-135