Immunoglobulin G4 (IgG4), Human Myeloma Plasma

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MW: 146,000 Da
Extinction Coefficient: 1.36

Frozen in 20 mM phosphate, pH 7.4, with 150 mM NaCl and 0.05% NaN3.

IgG4 antibodies will dominate the IgG response in schistosomiasis, lymphatic filariasis, and in patients after allergen immunotherapy. Unlike the other IgG subclasses, IgG4 does not activate complement. A combined IgA-IgG4 deficiency has been associated with recurrent pyogenic infections.

Storage: <= -20°C

Purity: >=95% by SDS-PAGE.

Prepared from myeloma plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.