Trypsin, Human Pancreas

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100 ug
$190.00
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PRODUCT NUMBER:

16-19-032000

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MW: 21,000-23,000
Extinction Coefficient: 1.45

Salt-free lyophilized from 2 mM HCl.

Hydrolyzes peptides, amides, and ester bonds involving the carboxyl groups of L-arginine or L-lysine. Increased serum values of this enzyme and/or its zymogen (trypsinogen) have been found in patients with cystic fibrosis. Trypsinogen has three isoforms: cationic (trypsinogen 1), anionic (trypsinogen 2, MW 22,500), and mesotrypsinogen (trypsinogen 3, MW, 25,000). The trypsin purified by Athens Research and Technology Inc. is the cationic form.


Activity: 2.5 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one umole of N-benzoyl-DL-arginine-pNA per minute at 25oC in 200 mM Tris-HCl, pH 7.8, with 20 mM CaCl2.

Storage: -20°C

Purity: >=95% by SDS-PAGE

Prepared from tissue shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.


Product Citation:
Kenninston JA, et al. Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody. J Biol Chem. 2014 Aug 22;289(34):23596-608. doi: 10.1074/jbc.M114.569061. Epub 2014 Jun 26.