Apolipoprotein E, Human Plasma

PRODUCT NUMBER:

MW: 34,000
Extinction Coefficient: 1.31

Frozen in 50 mM NH4HCO3, pH 8.0

Storage: <= -70°C

Bulk Qty available.
Researchers' source for Alzheimer's Disease Research.

Apolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions include immunoregulation and cell growth modulation and differentiation. Apo E is thought to be involved in tissue repair as increased amounts of the protein are found at sites of peripheral nerve injury and regeneration. A mutant form is associated with familial type III hyperlipoproteinemia. The concentration of Apo E in normal plasma is 5 mg per 100 ml.

Ref: Mahley, R.W. Science. 240,622.

Purity: >=95% by SDS-PAGE

Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.

Product Citation:
Guevara, Juan, Nagindra Prashad, Boris Ermolinsky, John W. Gaubatz, Dongcheul Kang, Andrea E. Schwarzbach, David S. Loose, and Natalia Valentinova Guevara. "Apo B100 similarities to viral proteins suggest basis for LDL-DNA binding and transfection capacity." Journal of lipid research51, no. 7 (2010): 1704-1718.