S-100 Protein, Bovine Brain
PRODUCT NUMBER:
16-BR-190816-bovineMW: 6000-6500 (Reduced/Heated)
Buffer: 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 100 μM DTT
Form: Lyophilized
Storage: <= -20ºC
Purity: >95% by SDS-PAGE
Biological Significance: S-100 is a low molecular weight, cytoplasmic, calcium binding protein. It is traditionally found in the brain, heart and muscle tissue. S-100 has two subunits (alpha-chain and beta-chain) and exists in several different forms. The alpha-alpha homodimer is referred to in literature as either the S-100αα or S-100a(0), the beta-beta homodimer is referred to in literature as S-100b and the alpha-beta heterodimer is referred to in literature as S-100a. ART purifies a mixture of all forms (S-100), S-100αα (<5% beta chain contamination by Western Blot), and S-100b (<10% alpha chain contamination by Western Blot).
References: Neurochemical Research 13, 561-565 (1988); J Biol Chem 261, 8204-8212 (1986); FEBS Lett 148, 231-234 (1982); Biochem Biophys ACTA 494, (1977), 222-232; J Biol Chem 246. 6276-6283 (1971)
Prepared from tissue collected in the contiguous United States from animals under 30 months of age at a USDA-inspected facility. Animals were inspected ante mortem and found free from obvious signs of infectious and contagious diseases.
Country of Origin: US
Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.