Apotransferrin, Human Plasma
PRODUCT NUMBER:
16-16-A32001MW: 80,000
Lyophilized from 10 mM phosphate buffer, pH 7.4.
Storage: <= -20°C
Bulk Qty Available.
Transferrin less the iron molecule. Like transferrin, apotransferrin has a physiological role in the transportation and distribution of iron among the body organs. It is also an important transport factor used in defined culture media. Purified to have less than 0.01% iron and an iron-binding capacity of 1.25 ug/mg. Dissolves in water at 10 mg per ml.
Ref: MacGillivray, R.T.A. et al. 1982 Proc. Natl. Acad. Sci. USA. 79,2504; Rivat,C. et al. 1992 J. Chromatogr. 576,71
Purity: >=95% by SDS-PAGE
Iron Content: <30 ug per gram
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.
Product Citation:
Mangano, K., et al. "The immunobiology of apotransferrin in type 1 diabetes." Clinical & Experimental Immunology 169.3 (2012): 244-252.
Sakamoto K, et al.
IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections.
Sci Immunol. 2017 Feb;2(8). pii: eaai8371. doi: 10.1126/sciimmunol.aai8371. Epub 2017 Feb 3.